Zhong hua yi xue za zhi, 2012-11, Vol.92 (41), p.2918-2920
2012
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- Autor(en) / Beteiligte
- Titel
- Baseline analysis of refractory primary biliary cirrhosis
- Ist Teil von
- Zhong hua yi xue za zhi, 2012-11, Vol.92 (41), p.2918-2920
- Ort / Verlag
- China
- Erscheinungsjahr
- 2012
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- To summarize the clinical characters of refractory primary biliary cirrhosis (PBC) versus typical ones and explore the risk factors of prognosis. From 2009 to 2011, 60 PBC patients on the therapy of ursodeoxycholic acid (UDCA) over 1 year at our clinic were recruited. According to the response to UDCA by the Paris criteria, they were divided into refractory group (n = 23) and typical group (n = 37) to analyze the basic clinical conditions, biochemical markers, antibodies and liver biopsies. (1) Compared with the typical patients, the refractory ones had more fatigue (73.9% vs 45.9%), pruritus (60.9% vs 40.5%) and jaundice (43.4% vs 18.9%); (2) the serum level of biomarkers (alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), γ-glutamyl transpeptidase (GGT), total bilirubin (TBIL), direct bilirubin (DBIL) and immunoglobulin M (IgM)) were higher in the refractory group (P < 0.05); (3) no differences existed between two groups in age, gender, antibodies (antinuclear anti
- Sprache
- Chinesisch
- Identifikatoren
- ISSN: 0376-2491DOI: 10.3760/cma.j.issn.0376-2491.2012.41.010Titel-ID: cdi_proquest_miscellaneous_1273662526