Details
- Autor(en) / Beteiligte
- Titel
- Cytotoxic Petrosiacetylenes from the Marine Sponge Petrosia sp
- Ist Teil von
- Lipids, 2013, Vol.48 (1), p.87-91
- Ort / Verlag
- Berlin/Heidelberg: Springer-Verlag
- Erscheinungsjahr
- 2013
- Link zum Volltext
- Quelle
- Wiley Blackwell Single Titles
- Beschreibungen/Notizen
- A novel petrosiacetylene analog (petrosiacetylene E) has been isolated from the Korean marine sponge Petrosia sp., along with petrosiacetylene A, B and C. Their structures were elucidated on the basis of spectroscopic methods and the stereochemistry of the new compound was determined by using the modified Mosher’s method. Petrosiacetylene E showed higher cytotoxicity against five human cancer cell lines than petrosiacetylene A and B, presumably due to the additional hydroxy group located at C-16.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0024-4201eISSN: 1558-9307DOI: 10.1007/s11745-012-3727-5Titel-ID: cdi_proquest_miscellaneous_1273167847
- Format
- –
- Schlagworte
- Animals, Antineoplastic Agents, Phytogenic - chemistry, Antineoplastic Agents, Phytogenic - isolation & purification, Antineoplastic Agents, Phytogenic - pharmacology, Biomedical and Life Sciences, Cell Line, Tumor, Cell Survival - drug effects, Communication, Cytotoxicity, Drug Screening Assays, Antitumor, Life Sciences, Lipidology, Medical Biochemistry, Medicinal Chemistry, Microbial Genetics and Genomics, Neoplasms - drug therapy, Neurochemistry, Nutrition, Petrosia, Petrosia - chemistry, Petrosiacetylene, Polyacetylenes - chemistry, Polyacetylenes - isolation & purification, Polyacetylenes - pharmacology, Polyacetylenic alcohol, Sponge