Details

Autor(en) / Beteiligte

• Moss, Arthur J
• Schuger, Claudio
• Beck, Christopher A
• Brown, Mary W
• Cannom, David S
• Daubert, James P
• Estes, N.A. Mark
• Greenberg, Henry
• Hall, W. Jackson
• Huang, David T
• Kautzner, Josef
• Klein, Helmut
• McNitt, Scott
• Olshansky, Brian
• Shoda, Morio
• Wilber, David
• Zareba, Wojciech

Titel

Reduction in Inappropriate Therapy and Mortality through ICD Programming

Ist Teil von

• The New England journal of medicine, 2012-12, Vol.367 (24), p.2275-2283

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2012

Quelle

MEDLINE

Beschreibungen/Notizen

• In this trial, two new programs for delivering implantable cardioverter–defibrillator therapy resulted in fewer inappropriate interventions (shocks or antitachycardia pacing) and an unexpected reduction in mortality. Improved programming could benefit patients with ICDs. The implantable cardioverter–defibrillator (ICD), either alone or in conjunction with cardiac-resynchronization therapy (CRT), is highly effective in reducing the rate of death due to ventricular tachyarrhythmia among high-risk cardiac patients. 1 – 4 However, inappropriate ICD activations, which are typically caused by supraventricular tachyarrhythmias, are frequent, despite sophisticated device-related detection algorithms that are designed to differentiate supraventricular from ventricular tachyarrhythmias; such activations have potentially life-threatening side effects. 5 , 6 Inappropriate device-delivered therapy, defined as therapy delivered for nonventricular tachyarrhythmias, affects 8 to 40% of patients with ICDs. 5 The best method for programming ICD devices to reduce inappropriate therapy is unknown. 7 We conducted a . . .