Neuroscience, 2012-10, Vol.223, p.163-173
2012
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- Autor(en) / Beteiligte
- Titel
- Glucocorticoid receptors and extinction retention deficits in the single prolonged stress model
- Ist Teil von
- Neuroscience, 2012-10, Vol.223, p.163-173
- Ort / Verlag
- Amsterdam: Elsevier Ltd
- Erscheinungsjahr
- 2012
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights ► Exposure to the full SPS protocol induces extinction retention (ER) deficits. ► Exposure to partial SPS protocols do not induce ER deficits. ► Exposure to full and partial SPS protocols enhance hippocampal and PFC GR levels. ► Exposure to full SPS induces maximal hippocampal GR enhancement. ► A threshold-enhancement in hippocampal GRs contributes to ER deficits in SPS.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0306-4522eISSN: 1873-7544DOI: 10.1016/j.neuroscience.2012.07.047Titel-ID: cdi_proquest_miscellaneous_1074767585
- Format
- –
- Schlagworte
- Animals, anxiety, Biological and medical sciences, Conditioning (Psychology), contextual modulation, Disease Models, Animal, extinction recall, Extinction, Psychological - physiology, Fear, Fundamental and applied biological sciences. Psychology, Gene Expression Regulation - physiology, Hippocampus - metabolism, infralimbic cortex, Male, Memory Disorders - etiology, Memory Disorders - pathology, Neurology, Prefrontal Cortex - metabolism, PTSD, Rats, Rats, Sprague-Dawley, Receptors, Glucocorticoid - metabolism, Stress, Psychological - complications, Swimming - psychology, Vertebrates: nervous system and sense organs