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Incidence of periprocedural myocardial infarction following stent implantation: Comparison between first- and second-generation drug-eluting stents
Catheterization and cardiovascular interventions, 2012-10, Vol.80 (4), p.524-530
Tandjung, Kenneth
Basalus, Mounir W.Z.
Muurman, Esther
Louwerenburg, Hans W.
van Houwelingen, K. Gert
Stoel, Martin G.
de Man, Frits H.A.F.
Jansen, Hanneke
Huisman, Jennifer
Linssen, Gerard C.M.
Droste, Herman T.
Nienhuis, Mark B.
von Birgelen, Clemens
2012
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Tandjung, Kenneth
Basalus, Mounir W.Z.
Muurman, Esther
Louwerenburg, Hans W.
van Houwelingen, K. Gert
Stoel, Martin G.
de Man, Frits H.A.F.
Jansen, Hanneke
Huisman, Jennifer
Linssen, Gerard C.M.
Droste, Herman T.
Nienhuis, Mark B.
von Birgelen, Clemens
Titel
Incidence of periprocedural myocardial infarction following stent implantation: Comparison between first- and second-generation drug-eluting stents
Ist Teil von
Catheterization and cardiovascular interventions, 2012-10, Vol.80 (4), p.524-530
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2012
Quelle
Wiley Online Library Journals Frontfile Complete
Beschreibungen/Notizen
Background: First‐ and second‐generation drug‐eluting stents (DES) differ in coating materials, which may influence the incidence of periprocedural myocardial infarction (PMI). Objective: To compare the incidence of PMI between first‐ and second‐generation DES, using the current Academic Research Consortium (ARC) definition of PMI. Methods: We assessed 800 patients treated with first‐ (Taxus Liberté or Endeavor) or second‐generation DES (Xience V or Resolute). Each DES group consisted of 200 consecutive patients, who were treated during the transition from first‐ to second‐generation DES. Routine peri‐interventional assessment of cardiac biomarkers was performed to compare the incidence of PMI between DES groups according to the updated definition by the ARC: 2x upper reference limit of creatine kinase (CK), confirmed by CK‐MB elevation. Results: In 800 patients, a total of 1,522 DES (363 Taxus; 385 Endeavor; 382 Xience V; 392 Resolute) were implanted to treat 1,232 lesions. Patient characteristics did not differ between groups. In patients receiving second‐generation DES, more multivessel percutaneous coronary interventions were performed (P = 0.01). The overall incidence of PMI was 4.75%. Between first‐ and second‐generation DES, there was no significant difference in PMI (5.5% vs. 4.0%; P = 0.29). In a multivariate analysis, only the total number of stents implanted (P < 0.001) and presentation with acute coronary syndrome (P = 0.02) were independent predictors of PMI. Conclusion: Using the revised ARC definition, we found no significant difference in PMI between first‐ and second‐generation DES. Overall, PMI occurred in 4.75%, which is 58% lower than with use of the historical PMI definition. © 2011 Wiley Periodicals, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 1522-1946
eISSN: 1522-726X
DOI: 10.1002/ccd.23334
Titel-ID: cdi_proquest_miscellaneous_1069205267
Format
–
Schlagworte
Aged
,
Biomarkers - blood
,
cardiac biomarkers
,
Cardiovascular Agents - administration & dosage
,
Chi-Square Distribution
,
coronary artery disease
,
Coronary Artery Disease - therapy
,
Creatine Kinase, MB Form - blood
,
drug-eluting stent
,
Drug-Eluting Stents
,
Female
,
Humans
,
Incidence
,
Logistic Models
,
Male
,
Middle Aged
,
Multivariate Analysis
,
Myocardial Infarction - blood
,
Myocardial Infarction - etiology
,
Netherlands - epidemiology
,
Odds Ratio
,
percutaneous coronary intervention
,
Percutaneous Coronary Intervention - adverse effects
,
Percutaneous Coronary Intervention - instrumentation
,
periprocedural myocardial infarction
,
Prosthesis Design
,
Retrospective Studies
,
Risk Assessment
,
Risk Factors
,
Time Factors
,
Treatment Outcome
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