Details

Autor(en) / Beteiligte

• Todd, John R.
• King, John W.
• Oberle, Arnold
• Matsumoto, Tadahiko
• Odaka, Yoshinobu
• Fowler, Marjorie
• Pore, R. Scott
• Shahan, Tracy Allan
• Yin, Lijia
• Sanusi, Irwan D.

Titel

Protothecosis: report of a case with 20-year follow-up, and review of previously published cases

Ist Teil von

• Medical mycology (Oxford), 2012-10, Vol.50 (7), p.673-689

Ort / Verlag

UK: Informa Healthcare

Erscheinungsjahr

2012

Quelle

Taylor & Francis Journals Auto-Holdings Collection

Beschreibungen/Notizen

• We present a Prototheca wickerhamii wound infection case that failed treatment with ketoconazole but was cured with amphotericin-B plus tetracycline. The patient was immunocompetent but had had local steroid injections. We reviewed another 159 cases from the literature. Prototheca has infected many areas of the human body, but most often skin, olecranon bursa, or wounds. Prior treatment with steroids and immune deficiencies are contributing factors. Itraconazole and fluconazole are reasonable initial treatments for patients with mild infections. For serious infections, or for infections that have failed azole treatment, amphotericin-B is the treatment of choice.