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A more detailed mechanism to explain the "bands of Fontana" in peripheral nerves
Ist Teil von
Muscle & nerve, 2012-10, Vol.46 (4), p.540-547
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2012
Quelle
Wiley Online Library Journals Frontfile Complete
Beschreibungen/Notizen
Introduction:
In 1779, Fontana identified transverse and oblique bands along peripheral nerves. Subsequent studies pointed alternatively to endoneural or perineural components as the cause. Our aim was to clarify these conflicting findings.
Methods:
Recoiling of the bands of Fontana was video‐recorded in the rat sciatic nerve. Computer‐assisted design (CAD) software was used to model the nerve by interference figures.
Results:
In vivo microdissection showed distinctive, black‐and‐white, closely packed bands in the perineurium, which differed from the widely spaced, translucent, dark/pale gray, staggered bands in the endoneurium. CAD merging of these 2 patterns produced images resembling the bands observed in vivo.
Conclusions:
Two repetitive structures with different characteristics, 1 in the perineurium and the other in the endoneurium, merge to give the appearance of these bands. Muscle Nerve 46: 540–547, 2012