Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
Morphological and molecular characterisation of Echinococcus granulosus from goat isolates in Iran
Ist Teil von
Acta tropica, 2012-08, Vol.123 (2), p.67-71
Ort / Verlag
Oxford: Elsevier B.V
Erscheinungsjahr
2012
Quelle
MEDLINE
Beschreibungen/Notizen
[Display omitted]
► There is limited information about the genotypes of E. granulosus in goats. ► This study was conducted on isolates of E. granulosus recovered from goats in Iran. ► The morphological characteristics and a partial sequencing of Co1 gene were studied. ► The results confirmed that goats were infected by the sheep (G1) and camel (G6) strains. ► Goats are a good intermediated host for the (G1) strain.
Hydatidosis is considered to be an important economic and human public health problem in Iran, where a variety of animals act as intermediate hosts. There is limited information about the genotypes of Echinococcus granulosus in goats. In this study, 20 isolates of E. granulosus obtained from goats were characterised by mitochondrial DNA sequencing and morphology of the metacestode. The mitochondrial cytochrome oxidase 1 sequences were evaluated, and the sequence analysis indicated two genotypes within the isolates. 17 samples were identified as G1 strain, and 3 isolates were identified as G6 strain. The results of the morphological studies support the findings of the molecular studies. Two types of rostellar hooks were observed in the goat isolates, in agreement with the strain identification. Type 1 hooks were morphologically similar to those of the common sheep strains, whereas the dimensions of the hooks in type 2 were similar to those normally found in the camel strain. The morphological results suggest that Echinococcus of goat origin is phenotypically similar to either the sheep (G1) or the camel (G6) strains. Further, these results suggest that the transmission of the G1 genotype between sheep and goats seems to be the predominant mode of transmission, but further work is required to verify this.