Chemical and Pharmaceutical Bulletin, 2012/07/01, Vol.60(7), pp.920-923
2012
Details
- Autor(en) / Beteiligte
- Titel
- Four New Dilignans from the Roots of Wikstroemia indica
- Ist Teil von
- Chemical and Pharmaceutical Bulletin, 2012/07/01, Vol.60(7), pp.920-923
- Ort / Verlag
- Japan: The Pharmaceutical Society of Japan
- Erscheinungsjahr
- 2012
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Phytochemical investigation of the roots of Wikstroemia indica led to the isolation of four new dilignans (1-4). Their structures were established on the basis of the spectroscopic data including UV, IR, high resolution-electron ionization-mass spectrometry (HR-ESI-MS), 1D- and 2D-NMR (1H-1H correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond correlation (HMBC) and rotating frame Overhauser enhancement spectroscopy (ROESY)). These dilignans were screened for their in vitro antiviral activities against respiratory syncytial virus (RSV) with cytopathic effect (CPE) reduction assay.
- Sprache
- Englisch; Japanisch
- Identifikatoren
- ISSN: 0009-2363eISSN: 1347-5223DOI: 10.1248/cpb.c12-00132Titel-ID: cdi_proquest_miscellaneous_1024938135
- Format
- –
- Schlagworte
- antiviral activity, Antiviral Agents - chemistry, Antiviral Agents - isolation & purification, Antiviral Agents - pharmacology, Cytopathogenic Effect, Viral - drug effects, dilignan, Magnetic Resonance Spectroscopy, Mass Spectrometry, Molecular Conformation, Plant Roots - chemistry, Respiratory Syncytial Viruses - drug effects, Thymelaeaceae, Wikstroemia - chemistry, Wikstroemia indica