Details

Autor(en) / Beteiligte

• Adams, Christopher J
• Bedford, Robin B
• Carter, Emma
• Gower, Nicholas J
• Haddow, Mairi F
• Harvey, Jeremy N
• Huwe, Michael
• Cartes, M. Ángeles
• Mansell, Stephen M
• Mendoza, Carla
• Murphy, Damien M
• Neeve, Emily C
• Nunn, Joshua

Titel

Iron(I) in Negishi Cross-Coupling Reactions

Ist Teil von

• Journal of the American Chemical Society, 2012-06, Vol.134 (25), p.10333-10336

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2012

Quelle

MEDLINE

Beschreibungen/Notizen

• Herein we demonstrate both the importance of Fe­(I) in Negishi cross-coupling reactions with arylzinc reagents and the isolation of catalytically competent Fe­(I) intermediates. These complexes, [FeX­(dpbz)2] [X = 4-tolyl (7), Cl (8a), Br (8b); dpbz = 1,2-bis­(diphenylphosphino)­benzene], were characterized by crystallography and tested for activity in representative reactions. The complexes are low-spin with no significant spin density on the ligands. While complex 8b shows performance consistent with an on-cycle intermediate, it seems that 7 is an off-cycle species.