Details

Autor(en) / Beteiligte

• Lima, Josivan Gomes de
• Nóbrega, Lúcia Helena Coelho
• Nóbrega, Maria Lúcia Coelho
• Santos Júnior, Antônio Correia dos
• Fernandes, Flávia da Costa
• Mesquita, Deciara Jácome Torres Medeiros de
• Souza, Alexandre Barbosa Câmara de

Titel

Influence of thyroid function in CPK serum levels

Ist Teil von

• Arquivos brasileiros de endocrinologia e metabologia, 2012-04, Vol.56 (3), p.190-194

Ort / Verlag

Brazil

Erscheinungsjahr

2012

Quelle

Elektronische Zeitschriftenbibliothek (Open access)

Beschreibungen/Notizen

• To determine serum CPK variation based on TSH e free T4 (FT4), and to assess serum CPK in pathological states of the thyroid (hyperthyroidism and hypothyroidism), in relation to the euthyroidism. We evaluated retrospectively 6,230 laboratory results of TSH and CPK from 2007 to 2011. From these, 3,369 had free T4 results. We evaluated the correlation between CPK and TSH and the pathological states of the thyroid. The correlation between TSH and CPK was positive (r = 0.065), while that between CPK and FT4 was negative (r = -0.091, p < 0.05). From the total of results analyzed, 586 (9.4%) were measures of hyperthyroidism, with a median (range) of CPK of 98 U/L (27 to 1,113), and 556 (8.9%) were of hypothyroidism, with CPK of 114 U/L (25-4,182). A positive correlation was found between serum CPK and TSH, and a negative correlation between CPK and FT4. CPK was lower in the group with hyperthyroidism, and greater in that with hypothyroidism.