Details

Autor(en) / Beteiligte

• Sommer, C.M
• Kortes, N
• Mogler, C
• Bellemann, N
• Holzschuh, M
• Arnegger, F
• Nickel, F
• Gehrig, T
• Zelzer, S
• Meinzer, H.P
• Longerich, T
• Stampfl, U
• Kauczor, H.U
• Radeleff, B.A

Titel

Super-micro-bland particle embolization combined with RF-ablation: Angiographic, macroscopic and microscopic features in porcine kidneys

Ist Teil von

• European journal of radiology, 2012-06, Vol.81 (6), p.1165-1172

Ort / Verlag

Ireland: Elsevier Ireland Ltd

Erscheinungsjahr

2012

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract Purpose To describe angiographic, macroscopic and microscopic features of super-micro-bland particle embolization in combination with RF-ablation in kidneys. Thereby, a special focus was given on the impact of the sequence of the different procedural steps. Materials and methods In ten pigs, super-micro-bland particle embolization combined with RF-ablation was carried out. Super-micro-bland embolization was performed with spherical particles of very small size and tight calibration (40 ± 10 μm). In the left kidneys, RF-ablations were performed before embolization (I). In the right kidneys, RF-ablations were performed after embolization (II). The animals were killed three hours after the procedures. Angiographic (e.g. vessel architecture), macroscopic (e.g. long and short axes of the RF-ablations) and microscopic (e.g. particle distribution) study goals were defined. Results Angiography detected almost no vessels in the center of the RF-ablations in I. In II, angiography could not define the RF-ablations. Macroscopy detected significantly larger long and short axes of the RF-ablations in II compared to I (52.2 ± 3.2 mm vs. 45.3 ± 6.9 mm [ P < 0.05] and 25.1 ± 3.5 mm vs. 20.0 ± 1.9 mm [ P < 0.01], respectively). Microscopy detected irregular particle distribution at the rim of the RF-ablations in I. In II, microscopy detected homogeneous particle distribution at the rim of the RF-ablations. Microscopy detected no particles in the center of the RF-ablations in I and II. Conclusion The sequence of the different procedural steps of super-micro-bland particle embolization combined with RF-ablation impacts angiographic, macroscopic and microscopic features in kidneys in the acute setting.