UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 21 von 125
Datensatz exportieren als...
BibTeX
Myogenic waves and myogenic programs during Xenopus embryonic myogenesis
Developmental dynamics, 2012-05, Vol.241 (5), p.995-1007
Della Gaspera, Bruno
Armand, Anne-Sophie
Sequeira, Inés
Chesneau, Albert
Mazabraud, André
Lécolle, Sylvie
Charbonnier, Frédéric
Chanoine, Christophe
2012
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Della Gaspera, Bruno
Armand, Anne-Sophie
Sequeira, Inés
Chesneau, Albert
Mazabraud, André
Lécolle, Sylvie
Charbonnier, Frédéric
Chanoine, Christophe
Titel
Myogenic waves and myogenic programs during Xenopus embryonic myogenesis
Ist Teil von
Developmental dynamics, 2012-05, Vol.241 (5), p.995-1007
Ort / Verlag
New York: Wiley-Liss, Inc
Erscheinungsjahr
2012
Quelle
Wiley Blackwell Single Titles
Beschreibungen/Notizen
Background: Although Xenopus is a key model organism in developmental biology, little is known about the myotome formation in this species. Here, we assessed the expression of myogenic regulatory factors of the Myod family (MRFs) during embryonic development and revealed distinct MRF programs. Results: The expression pattern of each MRF during embryonic development highlights three successive myogenic waves. We showed that a first median and lateral myogenesis initiates before dermomyotome formation: the median cell population expresses Myf5, Myod, and Mrf4, whereas the lateral one expresses Myod, moderate levels of Myogenin and Mrf4. The second wave of myoblasts arising from the dermomyotome is characterized by the full MRF program expression, with high levels of Myogenin. The third wave is revealed by Myf5 expression in the myotome and could contribute to the formation of plurinucleated fibers at larval stages. Furthermore, Myf5‐ or Myod‐expressing anlagen are identified in craniofacial myogenesis. Conclusions: The first median and lateral myogenesis and their associated MRF programs have probably disappeared in mammals. However, some aspects of Xenopus myogenesis have been conserved such as the development of somitic muscles by successive myogenic waves and the existence of Myf5‐dependent and ‐independent lineages. Developmental Dynamics 241:995–1007, 2012. © 2012 Wiley Periodicals, Inc. Key findings: The expression pattern of each myogenic regulatory factor (MRF) during embryonic development highlights three successive myogenic waves in Xenopus somites. A first median and lateral myogenesis initiates before dermomyotome formation in Xenopus. Xenopus craniofacial myogenesis is characterized by the presence of Myf5‐ or Myod‐lineages.
Sprache
Englisch
Identifikatoren
ISSN: 1058-8388
eISSN: 1097-0177
DOI: 10.1002/dvdy.23780
Titel-ID: cdi_proquest_miscellaneous_1002503484
Format
–
Schlagworte
Animals
,
dermomyotome
,
Gene Expression Regulation, Developmental
,
head muscles
,
Mrf4
,
Muscle Development - genetics
,
Muscle, Skeletal - embryology
,
Muscle, Skeletal - metabolism
,
Myf5
,
Myod
,
MyoD Protein - genetics
,
MyoD Protein - metabolism
,
myogenesis
,
Myogenic Regulatory Factor 5 - genetics
,
Myogenic Regulatory Factor 5 - metabolism
,
Myogenic Regulatory Factors - genetics
,
Myogenic Regulatory Factors - metabolism
,
Myogenin
,
Myogenin - genetics
,
Myogenin - metabolism
,
somites
,
Xenopus
,
Xenopus - embryology
,
Xenopus - genetics
,
Xenopus - metabolism
,
Xenopus Proteins - genetics
,
Xenopus Proteins - metabolism
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX