Details

Autor(en) / Beteiligte

• Jittimanee, Suphattra
• Ayudhya, Suparlark Nuntawan Na
• Kedkovid, Roongtham
• Teankum, Komkrich
• Thanawongnuwech, Roongroje

Titel

Genetic characterization and phylogenetic analysis of porcine circovirus type 2 in Thai pigs with porcine circovirus associated diseases (PCVAD) during 2007-2010

Ist Teil von

• Wētchasān sattawaphāet, 2011-06, Vol.41 (2), p.163

Ort / Verlag

Bangkok: Chulalongkorn University, Faculty of Veterinary Science

Erscheinungsjahr

2011

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Porcine circovirus type 2 (PCV2) was first recognized as a causative agent of post weaning multisystemic syndrome or PMWS in Canada in 1991. Subsequently, it has been reported in almost all intensive pig production countries, and currently all associated diseases linked to PCV2 are included under the term porcine circovirus associated diseases or PCVAD. PCV2 can be divided into 2 major genotypes referred to genotype 1 (PCV2b) and genotype 2 (PCV2a). In Thailand, PMWS was first reported in 1998. However, only one isolate of Thai PCV2 from our group has been submitted to GenBank (AY864814). Therefore, the objective of this study was to determine the genetic characterizations of 12 ORF2 of PCV2 isolates from Thai pigs with PCVAD during 2007-2010. Twelve Thai PCV2 sequences were analyzed together with 19 representative ORF2 sequences. Interestingly, all 12 recent Thai PCV2 sequences belong to genotype 1 consisting of subgroup 1A/B (10/12, 83.33%) and 1C (2/12, 16.67%). In summary, based on genetic characterization and phylogenetic analysis, a few specific substitution patterns were observed in amino acid positions and genotype 1, subgroup 1A/B was predominated in Thai pigs with PCVAD in this study. More samples are needed to investigate the existence of genotype 2. [PUBLICATION ABSTRACT]