Details

Autor(en) / Beteiligte

• Gupta, Soham
• Mishra, Baijayanti
• Muralidharan, Sethumadhavan
• Srinivasa, Hiresave

Titel

Ceftriaxone resistant Shigella Flexneri, an emerging problem

Ist Teil von

• Indian journal of medical sciences, 2010-12, Vol.64 (12), p.556

Ort / Verlag

Mumbai: Medknow Publications and Media Pvt. Ltd

Erscheinungsjahr

2010

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Shigellosis is a disease of public health importance in developing countries. It may cause self-limited diarrhea to severe dysentery. Emergence of multi drug resistant (MDR) strains is a growing concern globally. Ceftriaxone and ciprofloxacin are the drugs of choice for MDR cases. Here, we report a case of MDR Shigella flexneri from an immunocompromised patient. The strain was resistant to ceftriaxone [minimum inhibitory concentration (MIC) > 64 μg/ml], limiting the treatment option. Simultaneously, the strain was also found to be resistant to ciprofloxacin (MIC > 4 μg/ml). However, it was susceptible to ceftazidime (MIC 4 μg/ml). This is the first case of ceftriaxone resistant Shigella spp. reported from our hospital.