Details

Autor(en) / Beteiligte

• Gao, Wen‐Chao
• Yang, Jie
• Teng, Yong
• Li, Wen‐Dian
• Li, Wen‐Guang
• Li, Ting

Titel

Manganese‐Mediated Electrooxidative Ring‐Opening Azidation of Cyclobutanol Derivatives with TMSN3

Ist Teil von

• Advanced synthesis & catalysis, 2024-06, Vol.366 (11), p.2501-2506

Ort / Verlag

Heidelberg: Wiley Subscription Services, Inc

Erscheinungsjahr

2024

Link zum Volltext

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• A Mn‐electrocatalytic ring‐opening azidation of tert‐cyclobutanols has been developed. The regioselective method is applicable for the azidation of a diverse array of cyclobutanols to provide practical γ‐azido ketones in 23–91% yields under chemical oxidants‐free reaction conditions. Detailed mechanistic studies suggest the process of Mn‐mediated alkoxy radical generation followed by β‐scission to form carbon‐centered radical species is possibly involved in this transformation.