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Future directions and public health implications As we continue to explore the immunological basis of vaccines, there is growing recognition of the interconnectedness between infectious diseases, non-communicable diseases, and the environment. [...]the success of vaccination programs in eradicating or controlling once-devastating diseases like smallpox and polio serves as a testament to the power of immunization in shaping public health outcomes. Fatma M Ibrahim ="|fmibra@gmail.com Department of Health Science, Shanghai Jiao Tong University, China References 1 Hemachudha T, Laothamatas J, Rupprecht CE (2002) Human rabies a disease of complex neuro pathogenetic mechanisms and diagnostic challenges. 7 Fekadu M, Shaddock JH, Baer GM (1982) Excretion of rabies virus in the saliva of dogs.