Details

Autor(en) / Beteiligte

• Li, Wen-Yuan
• Hu, Cheng-Cheng
• Yao, Hui-Na
• Ren, Jia-Qian
• Li, Zi-Han
• Lu, Ling-Pan
• Qiao, Min
• Shan, Bing-Bing
• Li, Jin-Ge

Titel

Anti-MRSA Pyrone Derivative Products Isolated from Plant-Derived Fungus Aspergillus niger Pas67

Ist Teil von

• Chemistry of natural compounds, 2024, Vol.60 (3), p.415-418

Ort / Verlag

New York: Springer US

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A new pyrone derivative 11-hydroxypyrophen ( 1 ), together with pyrophen ( 2 ) and six naphtho-γ-pyrones ( 3 – 8 ), were obtained from the culture extract of Aspergillus niger Pas67. All isolated compounds were evaluated for their antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA). Compounds 4 and 8 showed significant antibacterial activity against MRSA with minimum inhibitory concentration values (MICs) of 25 and 16 μg/mL, while compounds 1 and 2 did not display anti-MRSA activity.