Details

Autor(en) / Beteiligte

• Davletshin, R. R.
• Galeev, R. R.
• Aryslanov, I. R.
• Galeeva, E. V.
• Sedov, A. N.

Titel

A Study of the Thermal Degradation of Amoxicillin Trihydrate Using Raman Spectroscopy and High-Performance Liquid Chromatography

Ist Teil von

• Journal of applied spectroscopy, 2024-05, Vol.91 (2), p.335-341

Ort / Verlag

New York: Springer US

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• High-performance liquid chromatography (HPLC) and Raman spectroscopy have been used to study the thermal degradation of amoxicillin trihydrate. Heating this compound at 60°C for 6 h led to an increase in the impurity contents, each not exceeding 1%. HPLC and Raman spectroscopy can be used to evaluate the quality of an amoxicillin sample obtained after thermal degradation at 80°C.