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The Lancet infectious diseases, 2024-05, Vol.24 (5), p.e290-e290
Ort / Verlag
London: Elsevier Ltd
Erscheinungsjahr
2024
Link zum Volltext
Quelle
Elsevier ScienceDirect Journals Complete
Beschreibungen/Notizen
In a mouse study, authors focused on a MOF called zeolitic imidazolate framework–8 (ZIF-8), which had previously been shown to generate an immune response, and created an experimental vaccine consisting of the SARS-CoV-2 receptor-binding domain embedded within ZIF-8 particles. Crimean-Congo haemorrhagic fever receptor found Crimean-Congo haemorrhagic fever virus (CCHFV) enters cells via low density lipoprotein receptors (LDLRs), according to research that found that mice lacking the LDLRs did not get as sick as others. CCHFV, which is spread through tick bites of the Hyalomma genus that are carried by migratory birds, causes disease with a mortality rate of up to 40%, according to WHO.