Details

Autor(en) / Beteiligte

• Cheng, Junfei
• Zhang, Jing
• He, Shipeng
• Li, Minyong
• Dong, Guoqiang
• Sheng, Chunquan

Titel

Inside Back Cover: Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD+ (Angew. Chem. Int. Ed. 12/2024)

Ist Teil von

• Angewandte Chemie International Edition, 2024-03, Vol.63 (12), p.n/a

Auflage

International ed. in English

Ort / Verlag

Weinheim: Wiley Subscription Services, Inc

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Reversible and spatiotemporal regulation of protein degradation is important for chemical biology and drug discovery. In their Research Article (e202315997), Guoqiang Dong, Chunquan Sheng et al. developed activator‐based photoswitchable proteolysis‐targeting chimera (PS‐PROTAC) for the optical control of NAMPT and NAD+ both in vitro and in vivo.