Details

Autor(en) / Beteiligte

• Liu, Xin‐Qian
• Huang, Peng‐Fei
• Xiong, Bi‐Quan
• Tang, Ke‐Wen
• Liu, Yu

Titel

K2S2O8‐Mediated Access to Alkylsulfonated Spiro[4,5] Trienones from N‐Arylpropiolamides with the Insertion of Sulfur Dioxide

Ist Teil von

• Advanced synthesis & catalysis, 2024-02, Vol.366 (3), p.488-493

Ort / Verlag

Heidelberg: Wiley Subscription Services, Inc

Erscheinungsjahr

2024

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• A four‐component reaction of N‐arylpropiolamides, Hantzsch esters, Na2S2O5 and water via a radical cascade cyclization process with the insertion of sulfur dioxide mediated by K2S2O8 is reported. A series of alkylsulfonated spiro[4,5] trienones are prepared up to 86% yield with a good functional group tolerance and substrate applicability. Preliminary mechanism experiments indicate that carbonyl oxygen of spiro[4,5] trienones originated from water.