Details

Autor(en) / Beteiligte

• Elhussieny, Fatma Mohamed
• Eladawy, Iman Ibrahim Mohamed
• Ahmad, Inass Hassan
• Mahmoud, Eman
• El-Khouly, Nashwa
• Elmohaseb, Ghada F
• Elsyed, Asmaa F
• Youssef, Eman M I
• Bayoumy, Eman S M
• Abd Elhamed, Sally Said

Titel

Hearing impairment in relation to vitamin D status in type 2 diabetic patients: A cross-sectional study

Ist Teil von

• Electronic journal of general medicine, 2023-10, Vol.20 (5), p.em526

Ort / Verlag

East Sussex

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Objectives: To evaluate the association of serum 25 hydroxy vitamin D (25OHD) and hearing impairment type 2 diabetes mellitus (T2DM) patients. In addition, we aimed to examine whether T2DM-associated hearing impairment is correlated with the severity of diabetes. Methods: The present case-control study recruited adult patients with T2DM and healthy controls. Using pure-tone stimuli, we used an audiometer to assess the hearing thresholds of air conduction in each ear separately. Results: 84 patients and 32 volunteers were included. The serum 25OHD was lower in T2DM patients than in healthy control (12.24±1.3 versus 23.19±5.69, respectively; p<0.001). The prevalence of vitamin D deficiency was 100% in the T2DM group, compared to 25% in the control group (p=0.001). T2DM patients exhibited higher hearing thresholds at all tested frequencies compared to the control group (p<0.001). Diabetic patients with hearing impairment had a significantly lower serum 25OHD than the normal hearing group (11.7±1.2 versus 12.6±1.2 ng/d; p=0.02). The multivariate analysis demonstrated that serum 25OHD level was an independent predictor of hearing loss among diabetic patients (β=-0.605; p=0.041). Conclusions: the present study highlights the potential role of vitamin D deficiency in developing hearing impairment in the setting of T2DM. We found a negative correlation between serum 25OHD level and air conduction thresholds at low-mid and high frequencies amongst patients with T2DM.