Details

Autor(en) / Beteiligte

• Boudhas, Sara Boudhas

Titel

308 Vulvar malignant melanoma about 02 cases and review of the literature

Ist Teil von

• International journal of gynecological cancer, 2023-09, Vol.33 (Suppl 3), p.A382-A383

Ort / Verlag

Oxford: BMJ Publishing Group LTD

Erscheinungsjahr

2023

Beschreibungen/Notizen

• Introduction/BackgroundPrimary malignant melanoma of the female genital tract is an extremely rare tumor, representing about 1% of melanomas, followed by vaginal, uterine and ovarian localization in order of frequency; and less than 200 cases of vulvar cancer have been described worldwide. It is often asymptomatic and has a poor prognosis; diagnosis requires a histological examination by targeted biopsy.MethodologyThis retrospective cohort study included 02 women with VD treated in chu hassan II Uni between 2022 and 2023. Clinicopathological characteristics, treatment, recurrence and survival data were collected. Overall and recurrence-free survival was estimated by the Kaplan-Meier methodResultsBoth patients had a visible vulvar lesion at the time of diagnosis, both patients are over 60 years of age, had vulvectomy plus curage, no local recurrence notedConclusionOur results show that even at an early clinical stage, malignancy is an aggressive disease associated with poor clinical outcomes due to the presence of distant metastases.Abstract #308 Figure 1Vulvar melanoma[Figure omitted. See PDF]DisclosuresVD was significantly associated with high-risk clinicopathologic features, including age, tumor thickness, ulceration, positive resection margins, and involved lymph nodes.