Details

Autor(en) / Beteiligte

• Minol, J
• Scheithauer, J
• Brockmann, H
• Sander, I
• Meißner, M
• Robbenmenke, C
• Schöndorf, T
• Medart, D
• Hansen, S
• Menon, A K

Titel

SUBPULMONARY SUPPORT OF FONTAN PATIENTS - FROM COMPUTER SIMULATION TO CLINICAL APPLICATION

Ist Teil von

• International journal of artificial organs, 2023-07, Vol.46 (7), p.407

Ort / Verlag

Milan: Wichtig Editore s.r.l

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Objectives: A novel venous cannula (VC) was designed as an additional component of the EXCOR-VAD™ (Berlin Heart) to improve sub-pulmonary hemodynamics as a bridge to transplant of patients suffering a failure of their subpulmonary Fontan-circulation. After clinical implementation, the need for an adjustment of the VC to address a larger number of smaller patients became obvious. We like here to describe the crucial part of different techniques of computer simulation in this process. Methods: After having interviewed several experts, their suggestions regarding an adjustment of the VC-shape for smaller patients were summarized by a computed model. In a three-dimensional simulation, its morphological compatibility with the anatomy of small patients (Body Surface Area: < 0.6 m2; Body Weight: < 15kg) was examined by a virtual fitting. The resultant model was subjected to a hemodynamic flow-simulation to assure proper function. Results: The virtual fitting revealed an optimal adjustment of the VC to smaller patients not only by a true-to-scale minimization of the former model, but also by the reduction of shape as crucial step. The hemodynamic flow-simulation demanded only a minimal modification. Conclusions: We achieved by this computer-simulated workflow a suitable approach for a new design of a VAD-cannula that allows optimal results in size, shape and function in the very specific issue of small patients suffering a failure of their subpulmonary Fontan-circulation.