Details

Autor(en) / Beteiligte

• Huang, Xiao-Hong
• Liu, Feng-Lin
• Fu, Ting-Feng
• Hu, Xiao
• Wang, Ya-Yu
• Liu, Bo
• Teng, Ming-Yu
• Huang, Guo-Li

Titel

Visible light-induced radical cascade acylmethylation/cyclization of 2-(allyloxy)arylaldehydes with α-bromo ketones: access to cyclic 1,5-dicarbonyl-containing chroman-4-one skeletons

Ist Teil von

• Organic & biomolecular chemistry, 2023-08, Vol.21 (33), p.6772-6777

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A novel photocatalytic protocol for effective and efficient synthesis of cyclic 1,5-diketones containing chroman-4-one skeletons in moderate to good yields via radical cascade acylmethylation/cyclization of 2-(allyloxy)arylaldehydes with α-bromo ketones has been described. This reaction features a broad substrate scope, good functional group tolerance, and metal- and oxidant-free conditions. An acylmethyl radical-triggered cascade cyclization was involved. A visible light-induced, metal- and oxidant-free procedure for the acylmethyl radical-triggered cascade cyclization of 2-(allyloxy)arylaldehydes with α-bromo ketones under mild reaction conditions is reported.