Details

Autor(en) / Beteiligte

• Shu, Penghua
• Xu, Ting
• Lou, Yueyue
• Ge, Yabing
• Lu, Xiaoqing
• Zhang, Pengpai

Titel

A New Monoterpene Rhamnoside from Cercis glabra Legumes

Ist Teil von

• Records of natural products, 2023-03, Vol.17 (2), p.335-342

Ort / Verlag

Gebze: ACG Publications

Erscheinungsjahr

2023

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• A new monoterpene rhamnoside, (+)-(R)-α-terpineol α-L-rhamnoside (1), along with ten known compounds (2–11) were obtained after purification of the ethanol extract of Cercis glabra legumes. Their structures were elucidated by spectroscopic evidence including NMR, optical rotatory dispersion (ORD), HR-ESI-MS and chemical hydrolysis. In the acetylcholinesterase inhibitory assay, compounds 3 and 8 showed high percentages of inhibition which were comparable to the activity of donepezil (a commercial drug, the positive control), and exhibited IC50 values of 0.488, 0.391 mg/mL. These bioactive components could be promising acetylcholinesterase inhibitors.