Details

Autor(en) / Beteiligte

• Zhao, Yiming
• Meloni, Fernanda
• Male, Louise
• Le Duff, Cécile S.
• Brittain, William D. G.
• Buckley, Benjamin R.
• Fossey, John S.

Titel

Synthesis of atropisomeric phosphino-triazoles and their corresponding gold( i ) complexes

Ist Teil von

• Organic Chemistry Frontiers, 2023-07, Vol.10 (14), p.3460-3466

Ort / Verlag

London: Royal Society of Chemistry

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The synthesis of atropisomeric phoshino-triazoles is disclosed. It was found that the introduction of a phosphine functionality onto the 5-position of a 1,2,3-triazole ring could be highly restrictive towards the rotation around a triazole-aryl bond. VT NMR and chiral HPLC studies demonstrated that rotation was restricted even at high temperatures. Gold( i ) chloride complexes of single-enantiomer phosphines were prepared and again demonstrated to be conformationally stable.