Details

Autor(en) / Beteiligte

• Ibrahem Aljabari, Fadhel
• Abdulkareem Almashhadani, Haider
• H. Jehad, Marowah
• M. Kadhim, Mustafa

Titel

Synthesis and Characterization of Molecularly Imprinted Polymers for Metronidazole by using Allyl Chloride and Allyl Bromide as Monomers

Ist Teil von

• Research journal of pharmacy and technology, 2023-02, Vol.16 (2), p.715-720

Ort / Verlag

Raipur: A&V Publications

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Metronidazole-MIPs were prepared by using (MDZ) as the template as well as allylchloride (AYC) or allylbromide (AYB) as monomer, used (TMPTA) tri-methylol propane tri-acrylate or ethylene glycol di-methyl acrylate (EGDMA) as cross-linker and initiator used (BP) benzyl peroxide. By using different plasticizers (di butyl Phthalate (DBPH), Nitrobenzene (NB), oleic acid (OA) and paraffin) for MDZ-MIP1 and (Di-butyl sebecate (DBS), Di-methyl acrylate (DMA), Tributylphosphate(TBP) and Tris(ethylhexyl phosphate (TEHP) ) for MDZ-MIP2. Membranes of MIPs were prepared in PVC matrix. The characterizations of each electrode were determined The Slope range from (55.083 - 43.711) mV/decade, Limit of Detection (8 X 10 -4- 2 X 10-6) and Linearity range of electrodes MIPs from (1 X 10-5 - 1 X 10 -1). Stable Signe of electrode pH from (2.5-9) and study the selectivity with additives of drugs synthesis (Glucose, Calcium stearate, sodium benzoate and benzoic acid) demonstrate strong selectivity.