Details

Autor(en) / Beteiligte

• Bui, Ha Thanh
• Hoang, Viet Huu
• Ngo, Toan Van
• Bui, Huy Vu

Titel

Etiology and Clinical Features of Bacterial Meningitis in Adults at National Hospital for Tropical Diseases during 2015–2018

Ist Teil von

• Japanese Journal of Infectious Diseases, 2023/03/31, Vol.76(2), pp.101-105

Ort / Verlag

Japan: National Institute of Infectious Diseases

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• To evaluate the etiology and clinical features of bacterial meningitis (BM) in adults during 2015–2018 in Vietnam, a retrospective study using 102 patients was performed at the National Hospital of Tropical Diseases. BM occurred throughout the year, peaking in July–September. A total of 80.4% BM patients were males over 40 years old. The proportion of patients with underlying diseases was 41.2% and those in contact with pigs or pork products was 30.4%. Common manifestations include stiff neck, Kernig’s sign, headache, fever/hypothermia, and altered consciousness. The cerebrospinal fluid (CSF) had high protein concentration (median: 3.2 g/L, range: 1.3–6.2) and leukocytes (median: 1,312 cell/mm3, range: 234–2,943). Moreover, 29.4% meningitis cases were associated with septicemia. Streptococcus suis was the main cause (72.5%), followed by Pneumococcus (6.8%) and a few other bacteria. Factors associated with S. suis risk were male sex (OR: 8.29, 95% CI: 2.83–24.33), over 40 years old (OR: 3.55, 95% CI: 1.28–9.87), drinking habits (OR: 3.78, 95% CI: 1.03–13.72), headache (OR: 6.19, 95% CI: 2.17–17.65), fever/hypothermia (OR: 5.17, 95% CI: 1.97–13.56) and ≥2.0 ng/mL procalcitonin (OR: 2.72, 95% CI: 1.07–6.89). Education on S. suis and nosocomial infection prevention, as well as pneumococcal vaccination use, should be continued.