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Engineering Photosynthetic Microbial Consortia for Carbon‐Negative Biosynthesis
Ist Teil von
Angewandte Chemie, 2023-04, Vol.135 (17), p.n/a
Ort / Verlag
Weinheim: Wiley Subscription Services, Inc
Erscheinungsjahr
2023
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
Microbial consortia consisting of phototrophs and heterotrophs have raised extensive attention due to their potential in sustainable biotechnology. The challenge remains in the selection of appropriate partners since most heterotrophic microorganisms cannot naturally use the intermediate carbohydrates secreted by autotrophic partners. In a recent study, the Ni Lab has developed a highly compatible autotrophic‐heterotrophic symbiotic system comprising Synechococcus elongatus and Vibrio natriegens. V. natriegens (the sucrose utilization module) shows a high degree of nutritional complementarity and culturing compatibility with the engineered S. elongatus (the CO2 sequestration module). The combination of both species channels CO2 into various valuable chemicals, enabling carbon‐negative biosynthesis.
Li et al. recently developed a highly compatible phototrophic community integrating a sucrose‐producing CO2 sequestration module and a super‐coupled module. By a simple alteration of the sucrose utilization module, four distinct products could be synthesized directly from channelling CO2 into various chemicals, thus enabling a carbon‐negative biosynthesis.