Details

Autor(en) / Beteiligte

• Meriç, Nermin
• Rafikova, Khadichakhan
• Zazybin, Alexey
• Güzel, Remziye
• Kayan, Cezmi
• Elma Karakaş, Duygu
• Dündar, Abdurrahman
• ISLAM, Sholpan
• Okumuş, Veysi
• Aydemir, Murat

Titel

Application of Half‐Sandwich Metal‐Phosphinite Compounds to Biological Activities: Determine the energies of the HOMO and LUMO levels

Ist Teil von

• Zeitschrift für anorganische und allgemeine Chemie (1950), 2023-01, Vol.649 (2), p.n/a

Ort / Verlag

Weinheim: Wiley Subscription Services, Inc

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Mononuclear transition metal complexes 1‐(furan‐2‐yl)ethyldiphenyl[dichloro(η6‐p‐cymene)ruthenium(II)]phosphinite, (2), 1‐(furan‐2‐yl)ethyldiphenyl[dichloro(η6‐benzene) ruthenium(II)] phosphinite (3), 1‐(furan‐2‐yl)ethyldipheny[chloro(η4‐1,5‐cyclooctadiene)rhodium(I)]phosphinite (4), 1‐(furan‐2‐yl)ethyldiphenyl[dichloro (η5pentamethylcyclopentadienyl)iridium (III)] phosphinite (5) were synthesized and characterized by microanalysis, infrared, MS, and NMR spectroscopy. The biological activities of the complexes were also tested. Compounds 2 and 5 were the best complexes at DPPH radical scavenging and reducing power activity at 73.27 % and 0.41 at 200 μg/mL, respectively. The highest antimicrobial activity exhibited by complex 3 as 14 mm inhibition zone against S. aureus. All of the complexes have cleaved the DNA from the double‐strand and exhibited three bands on gel electrophoresis. Moreover, cyclic voltammetry studies of the phosphinite complexes were carried out to determine the energies of the HOMO and LUMO levels as well as to estimate their electrochemical and some electronic properties.