Details

Autor(en) / Beteiligte

• Chenarani, Seddigheh
• Ebrahimi, Mahmoud
• Arabali, Vahid
• Beyramabadi, Safar Ali

Titel

Determination of Lorazepam Using the Electrocatalytic Effect of NiO/SWCNTs Modified Carbon Paste Electrode as a Powerful Sensor

Ist Teil von

• Topics in catalysis, 2022, Vol.65 (5-6), p.733-738

Ort / Verlag

New York: Springer US

Erscheinungsjahr

2022

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• An electrochemical approach was developed for monitoring lorazepam as an anxiety disorders drug in an aqueous solution. In this regard, NiO/SWCNTs was synthesized by a simple and one-pot strategy (chemical precipitation in this case) method. Afterward, the carbon paste electrode (CPE) was modified with NiO/SWCNTs for fabrication of a highly sensitive electrochemical sensor, and a new sensor was used for sensing lorazepam. The NiO/SWCNTs/CPE amplified the oxidation signal of lorazepam about 1.86 times at optimum conditions. A linear dynamic range of 0.1–280 µM with a detection limit of 50 nM was observed for sensing lorazepam using NiO/SWCNTs/CPE as an analytical tool. The NiO/SWCNTs/CPE successfully monitored lorazepam with a recovery range of 97.5–104.58% in real samples.