Details

Autor(en) / Beteiligte

• Dergez, Timea
• Poór, Viktória
• Anditi, Bernard Collins
• Kőnig-Péter, Anikó

Titel

An Efficient and Simple Breast Milk Sample Preparation to Detect Polycyclic Aromatic Hydrocarbons by Gas Chromatography-Mass Spectrometry

Ist Teil von

• Journal of analytical chemistry (New York, N.Y.), 2022-04, Vol.77 (4), p.513-518

Ort / Verlag

Moscow: Pleiades Publishing

Erscheinungsjahr

2022

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Polycyclic aromatic hydrocarbons ( PAHs ) can be extremely hazardous to human health due to their carcinogenicity and toxicity. Following mother exposure, a part of PAHs might be transferred into breast milk, and PAH exposure may results in adverse effects in breastfeeding infants. Chrysene, benzo(a,h)anthracene, benzo(b)fluoranthene and benzo(a)pyrene ( PAH4 ) are the most suitable indicators of PAHs in food. The aim of this work was to develop a sensitive and selective sample preparation method for the determination of PAH4 in breast milk using gas chromatography-mass spectrometry. The study compared different extraction methods of PAHs. The method was validated using parameters such as linearity, precision, accuracy, limit of detection ( LOD ) and limit of quantification ( LOQ ). The calibration curve was linear over the range of 0.5–50 ng/mL. The intra- and inter-day relative standard deviation values were less than 0.37%. The recovery values ranged between 99.97 and 99.99%. The LOD and LOQ values were found to be between 1.4 and 1.7 ng/mL and between 2.5 and 4 ng/mL, respectively.