Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
The preparation and application of UiO-66-NH
2
-
bis
(aminomethyl)-phosphinic acid are reported in this study. The supported phosphinic acid is designed via a multi-step post-synthesis modification of a Zr-based metal–organic framework (MOF), UiO-66-NH
2
. The MOF is initially functionalized with ethylamine, followed by formaldehyde (formation of imine group), and finally with hypophosphorous acid to generate UiO-66-NH–CH
2
CH
2
N(CH
2
PO
2
H
2
)
2
. The modified MOF is characterized by different techniques such as XRD, SEM–EDS, FT-IR, TGA, and porosimetry. The modified MOF is efficiently used as a multifunctional heterogeneous catalyst (available Brønsted/Lewis acid sites and Lewis base site) in the multicomponent reaction of Hantzsch. A synergistic effect between the phosphinic acid and the support is observed for the synthesis of polyhydroquinolines. The catalyst is easily recycled and successfully reused several times.
Graphic Abstract
An acidic-basic heterogeneous catalyst was prepared and characterized, and the performance of the catalyst was investigated for the synthesis of polyhydroquinoline derivatives.