Details

Autor(en) / Beteiligte

• Sathyananda, H. M.
• Prashanth, P. A.
• Prashanth, G. K.
• Dileep, M. S.
• Boselin Prabhu, S. R.
• Nagabhushana, B. M.
• Shivakumara, C.
• Nagendra, H. G.

Titel

Evaluation of antimycobacterial, antioxidant, and anticancer activities of CuO nanoparticles through cobalt doping

Ist Teil von

• Applied nanoscience, 2022, Vol.12 (1), p.79-86

Ort / Verlag

Cham: Springer International Publishing

Erscheinungsjahr

2022

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Here, we report the synthesis of cobalt-doped copper oxide nanoparticles (CuO–NPs) via combustion strategy with lime juice as a reductant at relatively low temperature of 600 °C and at shorter duration of 3 h. Powder X-ray diffraction (XRD) results revealed that, every compound was in monoclinic structure with space group C 12 /C 1 (No. 15) and average particle size were found to be 18–21 nm. These NPs were used to evaluate the antimycobacterial activity against “ Mycobacterium tuberculosis H37Rv ATCC 27294” , “ Mycobacterium abscessus ATCC 19977” , “ Mycobacterium fortuitum ATCC 6841” , “ Mycobacterium chelonae ATCC 35752” and anticancer activity on MDA-MB-231 . Antioxidant activity was evaluated by DPPH method. The results showed that, doping CuO with cobalt improved the antimycobacterial, anticancer and scavenging activities of CuO–NPs.