Details

Autor(en) / Beteiligte

• Ali, Mohamed Mahrous
• Mohamed, Basheer Hafez
• El Emaryi, Metwally Hasan
• Al Mageed, Ashraf Ahmed Abd

Titel

Expansion Capacity of Drug-Eluting Stents in Patients with Left Main Coronary Artery Disease: An Intravascular Ultrasound Guided Study

Ist Teil von

• Cardiometry, 2021-08 (19), p.117-122

Ort / Verlag

Moscow: Russian New University

Erscheinungsjahr

2021

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Aims: The aim of this study was to assess the expansion capacity of current commercially available Drug Eluting Stents (DES) with nominal diameters of 3.5-4.0mm in patients with Left Main disease. Materials and Methods: This study was conducted on 50 Patients who underwent percutaneous coronary intervention (PCI)for Left Main disease at Benha university hospitals and National Heart Institute. PCI was done with Drug Eluting Stents (DES) with large diameters of 3.5-4mm and post dilatation was done with non-compliant (NC) balloons with diameters of 4.55mm. Intravascular ultrasound (IVUS) was used to measure maximal stent diameter and area. Results: Three commercially available DESs were used in our study; XIENCE Xpedition™, Ultimaster™ and Onyx™. Maximal stent diameter was 4.5±0.3mm and diameter expansion index was 0.96±0.05. Maximal stent area was 14.67±2.06mm2 and area expansion index was 0.86±0.07mm2. On IVUS images, significantly more calcification< 90 ° was detected in the group with expansion index < 0.85 (68.4 percent versus 25.8%, P=0.003) compared to the group with expansion index >0.85. We found that DESs with diameters of 3.5-4.0mm can be expanded up to diameter of 5.3mm after post-dilation. No complications were reported in the studied patients, including perforation or stent fracture. Conclusion: Current DESs with nominal diameters of 3.5-4.0mm can be safely and effectively over-expanded to reach the predicted diameters in the left main, but the presence of calcification >90 may affect the achievement of the predicted area.