Details

Autor(en) / Beteiligte

• Xu, Chunhuan
• Chen, Shengyu
• Zhao, Jingjin
• Luo, Xiaoshu
• Zhao, Shulin

Titel

A DNAzyme-mediated target-initiated rolling circle amplification strategy based on a microchip platform for the detection of apurinic/apyrimidinic endonuclease 1 at the single-cell level

Ist Teil von

• Chemical communications (Cambridge, England), 2021-10, Vol.57 (84), p.1117-112

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2021

Quelle

MEDLINE

Beschreibungen/Notizen

• A DNAzyme-mediated target-initiated rolling circle signal amplification strategy based on a microchip platform was developed for detecting apurinic/apyrimidine endonuclease 1 (APE1) at the single-cell level. This strategy was applied to assays of lysate samples from HL-7702, HeLa and MCF-7 cells, with a detection limit of lower than 1 HeLa cell. A DNAzyme-mediated target-initiated rolling circle amplification strategy based on a microchip platform was developed for the detection of apurinic/apyrimidinic endonuclease 1 at the single-cell level.