Details

Autor(en) / Beteiligte

• Danilova, N. D.
• Geraskina, O. V.
• Diuvenji, E. V.
• Feofanov, A. V.
• Plakunov, V. K.
• Gannesen, A. V.

Titel

Inhibitory Effect of Norepinephrine on Biofilm Growth of the Human Skin Commensal Kytococcus schroeteri H01

Ist Teil von

• Microbiology (New York), 2021-09, Vol.90 (5), p.666-669

Ort / Verlag

Moscow: Pleiades Publishing

Erscheinungsjahr

2021

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• — This is the first report on the effect of norepinephrine on biofilms and planktonic cultures of a human skin commensal Kytococcus schroeteri H01. A dose-depending inhibitory effect of norepinephrine on K. schroeteri was shown after 24 and 72 h of incubation on PTFE cubes. The most pronounced effect was observed at 3.5 × 10 –7 M norepinephrine after 24 h of incubation (71 ± 13% of the control) and at 3.5 × 10 –6 M after 72 h (78 ± 10% of the control). Biofilms formed on glass in the presence of norepinephrine were thinner and flatter than in the controls. No significant effect of norepinephrine on metabolic activity of the cells in biofilms formed on PTFE cubes was revealed. Norepinephrine probably affects initial stages of the switching to biofilm lifestyle and matrix synthesis in K. schroeteri H01.