Details

Autor(en) / Beteiligte

• Yang, Qi-Liang
• Li, Yan-Yan
• Liu, Ying
• Ren, Tian-Xiang
• Guo, Liu-Cheng
• Wang, Dong-Chao
• Xie, Ming-Sheng
• Qu, Gui-Rong
• Guo, Hai-Ming

Titel

Electrochemically facilitated oxidative C–H amination enables access to fluorescent N9-fused tricyclic xanthines

Ist Teil von

• Organic Chemistry Frontiers, 2021-10, Vol.8 (19), p.5410-5417

Ort / Verlag

London: Royal Society of Chemistry

Erscheinungsjahr

2021

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• In this study, an environmentally benign electrochemical protocol for intramolecular oxidative amination is developed, which offers an efficient and sustainable route to access diverse fused tricyclic systems of pyrido[1,2- e ]purine-2,4-dione derivatives with pharmacological interest, exhibiting broad scope and generality (>50 examples, yields up to 99%). This electrochemical strategy features good functional group tolerance and permits access to compounds that were previously not achievable under thermal conditions. The photoluminescence properties of the representative N9-fused tricyclic xanthines have also been investigated.