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Reporting of High Flow Oxygen Therapy Interventions in Pediatric Respiratory Diseases : A Methodological Systematic Review
Ort / Verlag
ProQuest Dissertations & Theses
Erscheinungsjahr
2020
Quelle
ProQuest Dissertations & Theses A&I
Beschreibungen/Notizen
Background: The quality of the reporting of interventions in health research is generally poor, limiting the utility of study results. High flow oxygen therapy (HFOT) is a relatively novel multicomponent intervention used in children with acute respiratory conditions without an established evidence base. Objectives To evaluate the completeness and quality of the reporting of HFOT interventions across published studies. Search method: MEDLINE database was searched up to 31st July 2019. Selection criteria: Randomized controlled trials (RCTs) and observational studies of children with bronchiolitis, pneumonia or in acute respiratory failure whose main respiratory support was HFOT. Data collection: One reviewer extracted data on general study characteristics and on HFOT interventions according to an adapted version of the Template for Intervention Description and Replication (TIDieR) checklist, with data verification by a second reviewer. We selected a priori a set of core TIDieR items (items 3 - What Materials, 4 - What Procedures, 8 - When and How much and 9 - Tailoring). Data analysis: We performed a descriptive synthesis and assessed the completeness and quality of the reporting of HFOT interventions. Results: Of the 48 studies (8139 participants) included, 11 studies (23%) were RCTs and 37 studies (77%) were observational studies. 19 studies (40%) reported the use of HFOT exclusively in patients with bronchiolitis and 29 studies (60%) in patients with different respiratory conditions. Only 6 studies (12.5%) correctly reported more than 50% of core items and no study correctly reported all these items. The least correctly reported component of HFOT was the item on Tailoring, found in 8% of published studies. Conclusion: The reporting of HFOT interventions in children with acute respiratory diseases is generally poor. An effort to improve the reporting of this intervention in future studies may result in better-quality evidence and ultimately lead to the optimization of care of children in acute respiratory distress.