Details

Autor(en) / Beteiligte

• Ivanov, Ivo D.
• Stoykova, Silviya S.
• Burdzhiev, Nikola T.
• Pantcheva, Ivayla N.
• Atanasov, Vasil N.

Titel

Synthetic Cannabinoids 5F-QUPIC and MDMB-CHMICA in Plant Material - Identification and Quantification by Gas Chromatography - Mass Spectrometry (GC-MS), Nuclear Magnetic Resonance (NMR), and High-Performance Liquid Chromatography with Diode Array Detection (HPLC-DAD)

Ist Teil von

• Analytical letters, 2021-07, Vol.54 (16), p.2600-2610

Ort / Verlag

Abingdon: Taylor & Francis

Erscheinungsjahr

2021

Quelle

Taylor & Francis Journals Auto-Holdings Collection

Beschreibungen/Notizen

• The synthetic cannabinoids 5F-QUPIC and MDMB-CHMICA were sprayed on plant material intended for smoking and was seized as a criminal evidence. Their presence was confirmed by gas chromatography - mass spectrometry (GC-MS), and nuclear magnetic resonance (NMR). In the absence of analytical standards (indirect approach), the quantity of 5F-QUPIC in the herbal extract was determined by high-performance liquid chromatography with diode array detection (HPLC-DAD) based on total hydrolysis and measurement of the hydrolytic product (8-hydroxyquinoline) at 292 nm. The quantity of MDMB-CHMICA was determined using the ratio of 1 H-NMR signals of both compounds in methanol-d 4 . 5F-QUPIC and MDMB-CHMICA in the herbal mixture were determined by the validated HPLC-DAD protocol by a direct approach with standards.