Details

Autor(en) / Beteiligte

• Mészáros, Rebeka
• Márton, András
• Szabados, Márton
• Varga, Gábor
• Kónya, Zoltán
• Kukovecz, Ákos
• Fülöp, Ferenc
• Pálinkó, István
• Ötvös, Sándor B

Titel

Exploiting a silver-bismuth hybrid material as heterogeneous noble metal catalyst for decarboxylations and decarboxylative deuterations of carboxylic acids under batch and continuous flow conditions

Ist Teil von

• Green chemistry : an international journal and green chemistry resource : GC, 2021-07, Vol.23 (13), p.4685-4696

Ort / Verlag

Cambridge: Royal Society of Chemistry

Erscheinungsjahr

2021

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Herein, we report novel catalytic methodologies for protodecarboxylations and decarboxylative deuterations of carboxylic acids utilizing a silver-containing hybrid material as a heterogeneous noble metal catalyst. After an initial batch method development, a chemically intensified continuous flow process was established in a simple packed-bed system which enabled gram-scale protodecarboxlyations without detectable structural degradation of the catalyst. The scope and applicability of the batch and flow processes were demonstrated through decarboxylations of a diverse set of aromatic carboxylic acids. Catalytic decarboxylative deuterations were achieved on the basis of the reaction conditions developed for the protodecarboxylations using D 2 O as a readily available deuterium source. A silver-containing hybrid material is reported as a heterogeneous noble metal catalyst for protodecarboxylations and decarboxylative deuterations of carboxylic acids.