Details

Autor(en) / Beteiligte

• Patel, Jay M.
• Loebel, Claudia
• Saleh, Kamiel S.
• Wise, Brian C.
• Bonnevie, Edward D.
• Miller, Liane M.
• Carey, James L.
• Burdick, Jason A.
• Mauck, Robert L.

Titel

Tissue Engineering: Stabilization of Damaged Articular Cartilage with Hydrogel‐Mediated Reinforcement and Sealing (Adv. Healthcare Mater. 10/2021)

Ist Teil von

• Advanced healthcare materials, 2021-05, Vol.10 (10), p.n/a

Ort / Verlag

Weinheim: Wiley Subscription Services, Inc

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Wiley Blackwell Single Titles

Beschreibungen/Notizen

• In article number 2100315 by Robert L. Mauck and co‐workers, a hyaluronic acid (HA) system is used to modify the surface of damaged cartilage. This interdigitating microenvironment enhances the multi‐scale mechanics of degenerated cartilage, restoring the response of chondrocytes within. This modified tissue surface can then be used to improve the adhesion and behavior of stem cells, providing a route to “seal” cartilage defects. Together, this combined reinforcement and sealing may present an innovative therapy for the treatment of damaged cartilage.