Details

Autor(en) / Beteiligte

• Liem Nguyen Thanh
• Hoang‐Phuong Nguyen
• Ngo, Minh Duy
• Bui, Viet Anh
• Phuong T.M. Dam
• Hoa Thi Phuong Bui
• Doan Van Ngo
• Tran, Kien Trung
• Tung Thi Thanh Dang
• Duong, Binh Duc
• Phuong Anh Thi Nguyen
• styth, Nicholas
• Heke, Michael

Titel

In Reply

Ist Teil von

• Stem cells translational medicine, 2021-06, Vol.10 (6), p.827-828

Ort / Verlag

Oxford: Oxford University Press

Erscheinungsjahr

2021

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• 10‐12 We specified the number of mononuclear cells, CD34+ hematopoietic stem cells, and progenitor cells in the section “BMMNC transplantation”: “The average mononuclear cell and CD34+ cell counts per kg body weight were 42.3 × 106/kg and 2.6 × 106 for the first transplantation and 40.9 × 106/kg and 2.1 × 106 for the second transplantation, respectively.” Limitations in our study, such as no control group, were indeed highlighted in our article, and we also recommended that a future study including a control group is required to accurately conclude the benefit of stem cells in improving autism disorders. [...]our study demonstrated that repeated bone marrow mononuclear cell infusion via intrathecal route is safe and provides initial evidence for a significant improvement in clinical outcomes for children suffering from autism spectrum disorder, justifying a future randomized, fully controlled clinical trial.