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Propensity Adjusted Comparative Analysis of Radial and Femoral Access for Neurointerventional Treatments
Ist Teil von
Neurosurgery, 2020-12, Vol.67 (Supplement_1)
Ort / Verlag
Philadelphia: Wolters Kluwer Health, Inc
Erscheinungsjahr
2020
Link zum Volltext
Quelle
Oxford Journals 2020 Medicine
Beschreibungen/Notizen
INTRODUCTION Transradial artery (TRA) catherization for neuroendovascular procedures is effective and associated with less complications than transfemoral procedures. However, the majority of literature for TRA is limited to series with a high proportion of diagnostic procedures METHODS All patients with an endovascular intervention from 10/1/2018 to 12/31/2019 performed at a single center were retrospectively analyzed. Patients were grouped into two cohorts: TRA versus TFA access. Primary outcomes included complications and access site cross-over. Secondary outcomes analyzed were mean fluoroscopy time and contrast amount. RESULTS 579 neurointerventional treatments were performed during the 15-month period. 163 (28%) procedures were initially attempted via a TRA and the remaining 416 (72%) via TFA. Of the 163 attempted TRA procedures, 7 (4%) crossovers (4 aneurysm embolizations, 2 thrombectomies for acute stroke, and 1 AVM embolization with 6 crossing over to TFA) vs 13 (3.1%) (5 crossing over to TRA) in the TFA procedures occurred (P = .49). Of the 162 TRA treatments that were carried out accounting for crossovers, 80 (35%) were for aneurysmal embolization, 31 embolization (19%) of an AVM/AVF, 4 (3%) thrombectomies of an acute stroke, 9 (6%) carotid artery stenting/angioplasty, 8 (5%) tumor embolization, 24 (15%) middle meningeal artery embolization for cSDH, and 6 (4%) other neurointerventions. The TRA procedures were significantly different than the 417 TFA procedures performed, which included 143 (34%) thrombectomies for acute stroke (P < .001). A significantly greater fluoroscopy time (39 vs 30 minutes) and total contrast (156 vs 128 mL) were observed in the TRA procedures (P < .001). TFA procedures (N = 43,10%) were associated with a higher complication rate than TRA procedures (N = 5,4%) (P = .008); however, the majority of complications were mild with only 18 (3%) major complications including three in the TRA procedures and 15 in the TFA interventions. After eliminating thrombectomy patients and performing a propensity adjustment (age, gender, symptoms, procedure, pathology, sheath and catheter size) TRA catheterization was associated with decreased odds of a complication (OR 0.25,95% CI: 0.085-0.72, P = .011) and greater contrast amount (161 vs 140mL, P = .007), but no difference in fluoroscopy time (39 vs 35 minutes, P = .052) than TFA treatments. CONCLUSION TRA access for neuroendovascular interventions can be performed successfully and efficiently for a variety of procedures and for numerous pathologies, with fewer overall complications than the traditional TFA approach.