Details

Autor(en) / Beteiligte

• Zhuang, Shi‐Yi
• Tang, Yong‐Xing
• He, Cai
• Chen, Xiang‐Long
• Xue, Wei‐Jian
• Wu, Yan‐Dong
• Wu, An‐Xin

Titel

Copper‐catalyzed Reaction of Anthranils with Methyl Ketones: Site‐Selective C5‐Dicarbonylation of Anthranils

Ist Teil von

• Advanced synthesis & catalysis, 2021-02, Vol.363 (4), p.1137-1141

Ort / Verlag

Heidelberg: Wiley Subscription Services, Inc

Erscheinungsjahr

2021

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• A copper‐catalyzed site‐selective C5‐dicarbonylation reaction of anthranils has been developed for synthesis of 1,2‐dicarbonyl compounds using methyl ketone as a commercially available carbonylation reagent. This process represents the first example to implement the C5‐dicarbonylation of anthranils, which involves an oxidative Csp3‐H/Csp2‐H cross‐coupling reaction along with thermolytic N−O bond cleavage.