Details

Autor(en) / Beteiligte

• Tian, Wan‐Fa
• Zhu, Yao
• He, Yong‐Qin
• Wang, Mei
• Song, Xian‐Rong
• Bai, Jiang
• Xiao, Qiang

Titel

Hydroxyl Assisted, Photoredox/Cobalt Co‐catalyzed Semi‐Hydrogenation and Tandem Cyclization of o‐Alkynylphenols for Access to 2,3‐Dihydrobenzofurans

Ist Teil von

• Advanced synthesis & catalysis, 2021-02, Vol.363 (3), p.730-736

Ort / Verlag

Heidelberg: Wiley Subscription Services, Inc

Erscheinungsjahr

2021

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Herein, a hydroxyl assisted, photoredox/cobalt co‐catalyzed semi‐hydrogenation and tandem cyclization of o‐alkynylphenols is developed towards direct assembly of 2,3‐dihydrobenzofurans. Moderate to good yields were obtained for a range of sterically and electronically diverse 2‐propynolphenols under mild conditions. Mechanistic studies demonstrated the inevitable role of the alcoholic hydroxyl group with (Z)‐alkene as the real intermediate. Finally, a key low‐valent cobalt catalyzed intramolecular hydroetherification of alkene is proposed.