Details

Autor(en) / Beteiligte

• Núñez‐Enríquez, Juan C.
• Correa‐Correa, Víctor
• Flores‐Lujano, Janet
• Pérez‐Saldivar, María L.
• Jiménez‐Hernández, Elva
• Martín‐Trejo, Jorge A.
• Espinoza‐Hernández, Laura E.
• Medina‐Sanson, Aurora
• Cárdenas‐Cardos, Rocío
• Flores‐Villegas, Luz V.
• Peñaloza‐González, José G.
• Torres‐Nava, José R.
• Espinosa‐Elizondo, Rosa M.
• Amador‐Sánchez, Raquel
• Rivera‐Luna, Roberto
• Dosta‐Herrera, Juan J.
• Mondragón‐García, Javier A.
• González‐Ulibarri, Juana E.
• Martínez‐Silva, Sofía I.
• Espinoza‐Anrubio, Gilberto
• Duarte‐Rodríguez, David A.
• García‐Cortés, Luis R.
• Gil‐Hernández, Ana E.
• Mejía‐Aranguré, Juan M.

Titel

Extremely Low‐Frequency Magnetic Fields and the Risk of Childhood B‐Lineage Acute Lymphoblastic Leukemia in a City With High Incidence of Leukemia and Elevated Exposure to ELF Magnetic Fields

Ist Teil von

• Bioelectromagnetics, 2020-12, Vol.41 (8), p.581-597

Ort / Verlag

Hoboken: Wiley Subscription Services, Inc

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• It is important to study the relationship between extremely low‐frequency magnetic fields (ELF‐MFs) and childhood leukemia, particularly in locations with a high incidence of this neoplasm in children and an elevated exposure to ELF‐MF, such as Mexico City. The aim was to investigate the association between ELF‐MF exposure and the risk of B‐lineage acute lymphoblastic leukemia (B‐ALL). A case–control study was conducted in Mexico City during the period from 2010 to 2011. Residential 24‐h ELF‐MF measurements were obtained for 290 incident B‐ALL patients and 407 controls, aged less than 16 years. Controls were frequency‐matched by sex, age (±18 months), and health institution. The adjusted odds ratios (aOR) and 95% confidence intervals (CIs) were calculated. ELF‐MF exposure at <0.2 μT was used to define the reference group. ELF‐MF exposure at ≥0.3 μT was observed in 11.3% of the controls. Different ELF‐MF intensity cutoff values were used to define the highest exposure category; the highest exposure category for each cutoff value was associated with an increased risk of B‐ALL compared with the corresponding lower exposure categories. The aORs were as follows: ≥0.2 μT = 1.26 (95% CI: 0.84–1.89); ≥0.3 μT = 1.53 (95% CI: 0.95–2.48); ≥0.4 μT = 1.87 (95% CI: 1.04–3.35); ≥0.5 μT = 1.80 (95% CI 0.95–3.44); ≥0.6 μT = 2.32 (95% CI: 1.10–4.93). ELF‐MF exposure as a continuous variable (per 0.2 μT intervals) was associated with B‐ALL risk (aOR = 1.06; 95% CI: 1.01–1.12). In the present study, the proportion of children exposed to ≥0.3 μT is among the highest reported worldwide. Additionally, an ELF‐MF exposure ≥0.4 μT may be associated with the risk of B‐ALL. Bioelectromagnetics. © 2020 Bioelectromagnetics Society