Details

Autor(en) / Beteiligte

• Wei-min Huo
• Hong-ning, Su
• Guo-hua, Zhang
• Hong-bin, Wang

Titel

Reference Interval and Medical Decision-Making Level of Anti-Thyroid Peroxidase Antibody in Pregnant Women

Ist Teil von

• Revista argentina de clínica psicológica, 2020-01, Vol.29 (3), p.546

Ort / Verlag

Buenos Aires: FUNDACIÓN AIGLÉ

Erscheinungsjahr

2020

Quelle

Applied Social Sciences Index & Abstracts (ASSIA)

Beschreibungen/Notizen

• Objective: To determine the levels and positive rates of anti-thyroid peroxidase antibody (anti-TPO) in healthy non-pregnant and pregnant women, and to establish the reference interval and medical decision-making level for pregnant women in Shijiazhuang. Methods The samples of healthy non-pregnant and pregnant women in Shijiazhuang were collected, and MedCal 11.4.2.0 software was used to establish the reference interval and medical decision-making level of anti-TPO. Results: The anti-TPO positive rates of pregnant women at different ages varied significantly. The anti-TPO positive rates of pregnant women from 23 to 30 and from 31 to 40 years old were 6% and 14%, respectively. The reference interval for pregnant women was 9.18-78.2 IU/mL. The anti-TPO medical decision-making level for thyroid dysfunction in pregnant women was 43 IU/mL at which the sensitivity was 88.75% and the specificity was 92.75%. Conclusion: The pregnant women aged 31-40 years old have high anti-TPO positive rates. Given that the clinical decision-making values of anti-TPO kits from different manufacturers vary distinctively and there is no reference interval for pregnant women, each hospital needs to establish reference intervals and medical decision-making levels based on actual conditions.